Genelex System

Being a leader in genetic testing and molecular diagnostics, we deliver accurate, comprehensive results based on clinical validity and analysis. Genelex is a Clinical Improvements Laboratory Amendments Certified Lab and follows best practices for delivering the results. Using innovative analytic software, we perform superior quality testing and medication management at our well-furnished laboratory facility.

Genelex and Personalized Medicine

Genelex tests cytochromes (CYPs) and other genes, which are responsible for metabolizing most commonly prescribed medications.

While PGx is an important factor in drug metabolism, other factors such as age, lifestyle (e.g. smoking, alcohol consumption) and end-organ function (e.g. liver and kidney function) also play a role.

We provide pharmacist-produced reports that gives information on how to optimize medications, and providers get access to analytics software and a Clinical Decision Support Tool (CDST) to assist in determining medication options for each individual.

Once tested, each patient is classified as a: Poor Metabolizer, Intermediate Metabolizer, Normal Metabolizer, Rapid Metabolizer, or Ultra-rapid Metabolizer. These classifications describe a patient’s inherent drug metabolizing capacity.

Genelex’s pharmacogenetic testing combined with a CDST reveals drug-metabolizing gene variants—found in more than 90% of patients—to help healthcare providers and pharmacists.

Our reports include patient-specific information on potential drug-drug, drug-gene, and cumulative interactions mediated by the tested polymorphic drug metabolizing enzymes. The generated reports may inform providers with immediate insight into individual differences in their patients’ drug processing ability.

Pharmacogenetics Basics

Have you ever wondered why a medication works extremely well for some but may have side effects for others?

PGx testing may answer this question and many others. We all have unique, complex genetic characteristics. We typically think of these characteristics as what determines our eye color or hair color. Genetics may play a role in how we respond to medications.

Due to of these genetic differences, two people can take the same dose of the same drug but may respond in very different ways. For example, the drug might work very well for one person, but not at all for another. Or the drug might cause side effects for one person, but not for someone else.

In some cases, drug-related side effects may be serious or cause death – even though the drug was prescribed normally by the doctor and used correctly by the patient. People who take several different drugs face an even greater risk of dangerous side effects, especially if they are over 65 years of age.

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